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Dexmedetomidine Overdose in the Perioperative Setting Victor SB Jorden, Robert M Pousman, Mary M Sanford, Per AJ Thorborg, and Michael P Hutchens  Author information provided at the end of the text. Dr. Jorden is Associate Medical Director, Abbott Laboratories; Dr. Pousman is a paid investigator and speaker/consultant for Abbott Laboratories; Ms. Sanford and Dr. Thorborg [...]

ObjectivesTo systematically review the literature comparing the efficacy and safety of dexmedetomidine and midazolam when used for procedural sedation ConclusionsDexmedetomidine is a promising alternative to midazolam for use in procedural sedation.Dexmedetomidine provides more comfort during the procedure for the patient and clinician.If carefully titrated, the safety profiles are similar. For complete research article dex-vs-midazolamdownload

Babette Bais 1, Nina M Molenaar 2, Hilmar H Bijma 3, Witte J G Hoogendijk 4, Cornelis L Mulder 5, Annemarie I Luik 6, Mijke P Lambregtse-van den Berg 7, Astrid M Kamperman 8 PMID: 32217339DOI: 10.1016/j.jad.2020.03.014 Abstract Background: Maternal use of benzodiazepines during pregnancy is common and has increased over the last decades. In this systematic review and meta-analysis, we studied the literature to estimate the worldwide use of benzodiazepines before, during [...]

Joseph D Tobias 1 PMID: 22067985DOI: 10.1097/PCC.0b013e318238b81c Abstract Objectives: Although generally effective for sedation during noninvasive procedures, dexmedetomidine as the sole agent has not been uniformly successful for invasive procedures. To overcome some of the pitfalls with dexmedetomidine as the sole agent, there are an increasing number of reports regarding its combination with ketamine. This article provides a descriptive [...]

Natalie Behrle, MD, MS; Esma Birisci, MA; Jordan Anderson, PharmD; Sara Schroeder;and Abdallah Dalabih, MD, MBA OBJECTIVE This study seeks to evaluate the efficacy and safety of intranasal (IN) dexmedetomidine as a sedative medication for non-invasive procedural sedation. METHODS Subjects 6 months to 18 years of age undergoing non-invasive elective procedures were included. Dexmedetomidine (3 [...]

Arpita Kapur and Vinay Kapur1 Abstract Sedation in dentistry has been a controversial topic due to questions being raised over its safety, especially in dental chair. Dental fear and anxiety are not only common in children but also significantly prevalent among adults due to high intensity of pain. Sharing of airway between the anesthesiologist and the dentist [...]

Hassan M Yehia 1, Neville J McDonald 2, Sharon Aronovich 3, Richard Gardner 4, Marita R Inglehart 5 PMID: 30170843 Abstract Introduction: Research shows that a high percentage of endodontic patients are interested in receiving intravenous (IV) sedation. The objectives of this study were to assess endodontists' IV sedation-related education, attitudes, and professional behavior and to explore whether providing versus not offering IV sedation procedures was [...]

C. Dixon,1A. Aspinall,2S. Rolfe,3 and C. Stevens4 Purpose Propofol is an intravenous anaesthetic agent commonly utilised in general anaesthesia, however in sub-anaesthetic concentrations can be utilised to provide sedation through automated dosing of target-controlled infusion (TCI). TCI has been shown to provide accurate and stable predicted plasma and effect-site concentrations of propofol. A four-part mixed-method prospective study [...]

Hassan Abed⁎ pecial Care Dentistry (SCD) is defined as “an improvement of oral health of the individuals and groups in society who have a medical, physical, mental, psychological, social, intellectual, emotional, or sensory impairment or disability or, more often, a combination of a number of these factors” (Fiske, 2006). It tends to assess the oral health [...]