Dexmedetomidine versus Midazolam in Procedural Sedation. A Systematic Review of Efficacy and Safety

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Objectives
To systematically review the literature comparing the efficacy and safety of dexmedetomidine and midazolam when used for procedural sedation

Conclusions
Dexmedetomidine is a promising alternative to midazolam for use in procedural sedation.
Dexmedetomidine provides more comfort during the procedure for the patient and clinician.
If carefully titrated, the safety profiles are similar.

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